710
Anti- IL23A Antibody | FNab04256
- SKU:
- 710-FNab04256-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- IL23A Antibody | FNab04256 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 2G1
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Immunogen: interleukin 23, alpha subunit p19
synonyms: IL 23, IL 23 A, IL 23 subunit alpha, IL 23A, IL 23p19, IL23A, IL23P19, Interleukin 23 subunit alpha, Interleukin 23 subunit p19, P19, SGRF
Molecular weight (observed) : 21 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200
Research Area: Immunology, Signal Transduction, Developmental biology