Anti- KANK2 Antibody | FNab04464

Anti- KANK2 Antibody | FNab04464 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081) . May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500) . May be involved in promotion of cell proliferation (By similarity) .

Immunogen: KN motif and ankyrin repeat domains 2

synonyms: ANKRD25, KIAA1518, MXRA3, SIP

Molecular weight (observed) : 95 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IF, IHC, WB

Recomended Dillution : IHC: 1:20-1:200; IF: 1:20-1:200

Research Area: Signal Transduction