Anti- KDM2A Antibody | FNab04509

Anti- KDM2A Antibody | FNab04509 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono-and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.

Immunogen: lysine (K) -specific demethylase 2A

synonyms: CXXC8, FBL7, FBXL11, JHDM1A, KIAA1004

Molecular weight (observed) : 126 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IP, IHC

Recomended Dillution : WB: 1:500-1:2000

Research Area: Epigenetics, Cancer, Metabolism