710
Anti- KDM2A Antibody | FNab04509
- SKU:
- 710-FNab04509-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- KDM2A Antibody | FNab04509 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono-and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.
Immunogen: lysine (K) -specific demethylase 2A
synonyms: CXXC8, FBL7, FBXL11, JHDM1A, KIAA1004
Molecular weight (observed) : 126 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB, IP, IHC
Recomended Dillution : WB: 1:500-1:2000
Research Area: Epigenetics, Cancer, Metabolism