Anti- LAT Antibody | FNab04706

Anti- LAT Antibody | FNab04706 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Required for TCR (T-cell antigen receptor) -and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III) -mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Immunogen: linker for activation of T cells

synonyms: LAT, LAT1, p36 38, pp36

Molecular weight (observed) : 36-38 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, IF, WB

Recomended Dillution : WB: 1:200-1:1000; IHC: 1:20-1:200

Research Area: Immunology, Signal Transduction