710
Anti- LONP1 Antibody | FNab04821
- SKU:
- 710-FNab04821-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- LONP1 Antibody | FNab04821 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 9H10
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.
Immunogen: lon peptidase 1, mitochondrial
synonyms: PRSS15
Molecular weight (observed) : 100 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP, IF
Recomended Dillution : WB: 1:500-1:10000; IHC: 1:400-1:1600; IF: 1:10-1:100
Research Area: Metabolism