Anti- LONP1 Antibody | FNab04821

Anti- LONP1 Antibody | FNab04821 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 9H10

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.

Immunogen: lon peptidase 1, mitochondrial

synonyms: PRSS15

Molecular weight (observed) : 100 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP, IF

Recomended Dillution : WB: 1:500-1:10000; IHC: 1:400-1:1600; IF: 1:10-1:100

Research Area: Metabolism