710
Anti- LRWD1 Antibody | FNab04867
- SKU:
- 710-FNab04867-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- LRWD1 Antibody | FNab04867 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
Immunogen: leucine-rich repeats and WD repeat domain containing 1
synonyms: CENP-33, ORCA
Molecular weight (observed) : 85 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : WB: 1:500-1:2000
Research Area: Developmental biology