Anti- MAD2L1 Antibody | FNab04924

Anti- MAD2L1 Antibody | FNab04924 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 8G6

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

Immunogen: MAD2 mitotic arrest deficient-like 1 (yeast)

synonyms: HSMAD2, MAD2, MAD2 like protein 1, MAD2L1

Molecular weight (observed) : 25-30 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IP

Recomended Dillution : WB: 1:1000-1:3000; IHC: 1:20-1:200

Research Area: Cell Division and Proliferation