710
Anti- MBNL3 Antibody | FNab05041
- SKU:
- 710-FNab05041-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- MBNL3 Antibody | FNab05041 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM) . Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.
Immunogen: muscleblind-like 3 (Drosophila)
synonyms: CHCR, MBLX39, MBXL
Molecular weight (observed) : 38 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200
Research Area: Developmental biology