Anti- MCRS1 Antibody | FNab05067

Anti- MCRS1 Antibody | FNab05067 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 5G3

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183) . As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852) . Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100) . Binds to G-quadruplex structures in mRNA (PubMed:16571602) . Binds to RNA homopolymer poly (G) and poly (U) (PubMed:16571602) .

Immunogen: microspherule protein 1

synonyms: INO80Q, MSP58

Molecular weight (observed) : 55 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:2000

Research Area: Metabolism