Anti- MGEA5 Antibody | FNab05164

Anti- MGEA5 Antibody | FNab05164 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 9B9

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Isoform 1: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:11148210) . Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714) . Isoform 3: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro), but has about six times lower specific activity than isoform 1.

Immunogen: meningioma expressed antigen 5 (hyaluronidase)

synonyms: HEXC, KIAA0679, MEA5

Molecular weight (observed) : 130 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IF, IP

Recomended Dillution : WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Research Area: Metabolism