Anti- MLF1 Antibody | FNab05210

Anti- MLF1 Antibody | FNab05210 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Immunogen: myeloid leukemia factor 1

synonyms: N/A

Molecular weight (observed) : 31 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Research Area: Cancer, Metabolism, Developmental biology