Anti- MME, CD10 Antibody | FNab05232

Anti- MME, CD10 Antibody | FNab05232 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 1H6

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: MME is also names as neprilysin, CALLA, NEP, SFE, CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas (PMID:15286660) .This antibody is specific to MME.

Immunogen: membrane metallo-endopeptidase

synonyms: Atriopeptidase, CALLA, CD10, DKFZp686O16152, Enkephalinase, EPN, membrane metallo endopeptidase, MME, NEP, Neprilysin, Neutral endopeptidase, Neutral endopeptidase 24.11

Molecular weight (observed) : 90-110 kDa

Reactivity Species: Human, Pig

Tested Application: ELISA, WB, IF, FC

Recomended Dillution : WB: 1:500-1:5000; IHC: 1:20-1:200

Research Area: Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells