Anti-MMP3 recMAb™ Antibody | A2183

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive pro-proteins, which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes that localize to chromosome 11q22.3.

A2183 | Anti-MMP3 recMAb™ Antibody DataSheet

Antibody Target: MMP3

Target Alternative Name: CHDS6, Matrix metalloproteinase 3, Matrix metalloproteinase-3, Proteoglycanase, SL1, STMY1, STR1, Stromelysin-1, Transin 1, STMY, MMP-3

Tag Line: Recombinant mouse monoclonal antibody to detect MMP3 expression in human samples

Category: Primary antibody

Host: Mouse

Isotype: IgG1, kappa

Species Reactivities: Human

Immunogen Sequence: Recombinant full-length human MMP3 protein

Accession #: P08254

Gene ID: 4314

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In 10 mM PBS

Purification: Protein A/G purified

Application: Immunohistochemistry (IHC)

Positive Control:

Application And Usages: IHC (1-2 µg/ml)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE