Anti-Mouse CD117 Monoclonal Antibody (FITC Conjugated) | DL21056F

Anti-Mouse CD117 Monoclonal Antibody (FITC Conjugated) | DL21056F | Gentaur UK, US & Europe Distribution

Host: Rat

Synonyms: Mast/stem cell growth factor receptor Kit, Kit, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, CD117

Reactivity: Mouse

Application: FCM

Background: CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR) . It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor) . CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Concentration: 0.5 mg/mL

Conjugation: FITC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: 2B8

Isotype: Rat IgG2b, κ