Anti-Mouse CD132 Monoclonal Antibody (PE Conjugated) | DL20289F

Anti-Mouse CD132 Monoclonal Antibody (PE Conjugated) | DL20289F | Gentaur UK, US & Europe Distribution

Host: Rat

Synonyms: Cytokine receptor common subunit gamma, Il2rg, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132

Reactivity: Mouse

Application: FCM

Background: CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID) .

Concentration: N/A

Conjugation: PE

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: 3E12

Isotype: Rat IgG2b, κ