Anti-Mouse CD45.2 Monoclonal Antibody (AF647 Conjugated) | DL21541F

Anti-Mouse CD45.2 Monoclonal Antibody (AF647 Conjugated) | DL21541F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Ly-5.2, LCA

Reactivity: Mouse

Application: FCM

Background: CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129) . CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Concentration: 0.5 mg/mL

Conjugation: AF647

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: 104, 2

Isotype: Mouse IgG2a, κ