Anti- MPRIP Antibody | FNab05296

Anti- MPRIP Antibody | FNab05296 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

Immunogen: myosin phosphatase Rho interacting protein

synonyms: KIAA0864, MRIP, RHOIP3

Molecular weight (observed) : 116-140 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IHC

Recomended Dillution : WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

Research Area: Signal Transduction