710
Anti- MSL1 Antibody | FNab05379
- SKU:
- 710-FNab05379-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- MSL1 Antibody | FNab05379 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub) . This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.
Immunogen: male-specific lethal 1 homolog (Drosophila)
synonyms: MSL1L1
Molecular weight (observed) : 67 kDa
Reactivity Species: Human
Tested Application: ELISA, IF, WB
Recomended Dillution : WB: 1:500-1:2000
Research Area: Developmental biology