Anti-MUM1/IRF4 Rabbit Monoclonal Antibody (RM352) | A1857

Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

A1857 | Anti-MUM1/IRF4 Rabbit Monoclonal Antibody (RM352) DataSheet

Antibody Target: MUM1/IRF4 (Multiple myeloma oncogene 1) (Interferon regulatory factor 4)

Target Alternative Name:

Tag Line: Affinity purified Rabbit monoclonal to MUM1/IRF4

Category: Primary antibody

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human

Immunogen Sequence: A peptide corresponding to the C-terminus of human MUM1/IRF4.

Accession #: Q15306

Gene ID: 3662

Appearance: Liquid

Form: Liquid

Concentration:

Formulation: 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Protein A affinity purified from an animal origin–free culture supernatant

Application: Western Blot: 1:1000-1:2000, IHC: 1:200-1:800

Positive Control:

Application And Usages: Western Blot: 1:1000-1:2000, IHC: 1:200-1:800

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: True

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False