Anti- NCOA6 Antibody | FNab05591

Anti- NCOA6 Antibody | FNab05591 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist-and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs) . Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Immunogen: nuclear receptor coactivator 6

synonyms: AIB3, KIAA0181, RAP250, TRBP

Molecular weight (observed) : 68 kDa ; 219 kDa ; 110 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IF

Recomended Dillution : IP: 1:200-1:2000

Research Area: Metabolism