Anti- NENF Antibody | FNab05661

Anti- NENF Antibody | FNab05661 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 7C8

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity) . Plays a role in the human tumorigenesis (PubMed:22748190) .

Immunogen: neuron derived neurotrophic factor

synonyms: CIR2, NENF, NEUDESIN, SCIRP10, SPUF, SPUF protein

Molecular weight (observed) : 18 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500

Research Area: Neuroscience