710
Anti- NFIL3 Antibody | FNab05700
- SKU:
- 710-FNab05700-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- NFIL3 Antibody | FNab05700 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity) . Represses transcriptional activity of PER1 (By similarity) . Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity) . Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity) . Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity) . Protects pro-B cells from programmed cell death (By similarity) .
Immunogen: nuclear factor, interleukin 3 regulated
synonyms: E4BP4, IL3BP1
Molecular weight (observed) : 55-60 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:2000
Research Area: Neuroscience, Metabolism