26
Anti-NFKBIE Antibody | A1762
- SKU:
- 26-A1762-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. NFKBIE protein expression is up-regulated following NF-?B activation and during myelopoiesis. NFKBIE is able to inhibit NF-?B-directed transactivation via cytoplasmic retention of REL proteins. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NF-?B transcription factor complex. The NF-?B complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm.
A1762 | Anti-NFKBIE Antibody DataSheet
Antibody Target: NF-kappa-B inhibitor epsilon
Target Alternative Name: I kappa B epsilon, IKBE, IKBE, mgC72568, NF kappa B inhibitor epsilon, Slc35b2
Tag Line: Polyclonal antibody to detect NF-kappa-B inhibitor epsilon in human and mouse samples.
Category: Signal Transduction
Host: Rabbit
Isotype: IgG
Species Reactivities: Mouse, Human
Immunogen Sequence: Recombinant protein of human NFKBIE
Accession #: O00221
Gene ID: 4794
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.3 mg/ml
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Application: Immunohistochemistry (IHC), Western Blotting, ELISA
Positive Control:
Application And Usages: WB 1:200-1:1000, IHC 1:50-1:200
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: True
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
Additional Information
Size: |
100 uL |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |