Anti- NLRP2 Antibody | FNab05758

Anti- NLRP2 Antibody | FNab05758 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Immunogen: NLR family, pyrin domain containing 2

synonyms: NALP2, NBS1, PAN1, PYPAF2

Molecular weight (observed) : 105-110 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, IHC, WB

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200

Research Area: Immunology