Anti-NT-proBNP (12-16) Detection Antibody | A2115

Natriuretic peptides are hormones that are produced by the cardiac tissues and are involved in functions such as maintaining homeostasis of body fluids and regulating blood pressure. There are three major known natriuretic peptides: Atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP) and C-type NP. BNP is first synthesized as pre-proBNP in the myocardium of the ventricle, which is then cleaved first to proBNP, then to active BNP (34 amino acids) and an inactive N-terminal proBNP (NT-proBNP). Although BNP and NT-proBNP are secreted in equal concentrations, NT-proBNP has a half-life of 120 mins. Increased levels of NT-proBNP are found with increased age, hypertrophy of the ventricles, fibrillation the atria and heart failure. Therefore NT-proBNP serves as an important diagnostic marker for cardiac failure.

A2115 | Anti-NT-proBNP (12-16) Detection Antibody DataSheet

Antibody Target: NT-proBNP

Target Alternative Name:

Tag Line: Mouse monoclonal antibody to detect N-terminal-pro hormone BNP (NT-proBNP). This antibody can be match paired with Anti-NT-proBNP (61-64) Capture Antibody (Catalog# A2114) and be used for applications such as Lateral Flow

Category: Primary antibody

Host: Mouse

Isotype:

Species Reactivities:

Immunogen Sequence: Native Human ProBNP antigen

Accession #:

Gene ID:

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 10 mM PBS, pH 7.4

Purification: >90%

Application: Lateral Flow

Positive Control:

Application And Usages: Lateral Flow

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE