BW
Anti-PANK2 monoclonal Antibody | MB62346
- SKU:
- BW-MB62346
- Availability:
- Usually ships in 5 working days
Description
Anti-PANK2 monoclonal Antibody | MB62346 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IF, IHC, WB
Application Range: WB 1:2000, IHC 1:150, IF 1:100
Background: This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq]
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: pantothenate kinase 2
Molecular Weight: 59.1 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: C20orf48; HARP; HSS; NBIA1; PKAN
Immunogen: Full length human recombinant protein of human PANK2 (NP_705902) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A