710
Anti- PARP3 Antibody | FNab06158
- SKU:
- 710-FNab06158-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- PARP3 Antibody | FNab06158 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Immunogen: poly (ADP-ribose) polymerase family, member 3
synonyms: ADPRT3, ADPRTL3
Molecular weight (observed) : 60-62 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Research Area: Metabolism