Anti- PDCD4 Antibody | FNab06240

Anti- PDCD4 Antibody | FNab06240 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 3B7

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity) .

Immunogen: programmed cell death 4 (neoplastic transformation inhibitor)

synonyms: H731, Nuclear antigen H731 like, PDCD4, Protein 197/15a

Molecular weight (observed) : 56 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, FC, IP

Recomended Dillution : WB: 1:1000-1:4000; IHC: 1:20-1:200

Research Area: Metabolism