Anti-Phospho-AKT1 (Y315) / AKT2 (Y316) / AKT3 (Y312) Polyclonal Antibody | A2347

The human AKT serine-threonine kinase family consists of three members (AKT1, AKT2, and AKT3) that are phosphorylated by phosphoinositide 3-kinase (PI3K) upon activation of cell membrane-associated signaling molecules such as receptor tyrosine kinases. AKT proteins regulate a wide variety of cellular functions including cell proliferation, survival, metabolism, and angiogenesis. Mutations in AKT are associated with multiple forms of cancer and hyperplasia.

A2347 | Anti-Phospho-AKT1 (Y315) / AKT2 (Y316) / AKT3 (Y312) Polyclonal Antibody DataSheet

Antibody Target: Human AKT1 / AKT2 / AKT3 phosphorylated at Y315 / Y316 / Y312

Target Alternative Name: PKB; Protein Kinase B; Protein Kinase B Beta; Protein Kinase B Gamma

Tag Line: A family of oncogenes that acts as critical factors in signaling pathways

Category: GM-CSF

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human

Immunogen Sequence: A phospho specific peptide corresponding to residues surrounding Y315 of human AKT1

Accession #: P31749 (AKT1); P31751 (AKT2); Q9Y243 (AKT3)

Gene ID: 207 (AKT1); 208 (AKT2); 10000 (AKT3)

Appearance: Liquid

Form: Rabbit polyclonal

Concentration:

Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Purification: Affinity purification

Application: Western Blotting

Positive Control:

Application And Usages: Western Blotting

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: TRUE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE