710
Anti- PKM Antibody | FNab06493
- SKU:
- 710-FNab06493-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- PKM Antibody | FNab06493 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Immunogen: PKM2 pyruvate kinase, muscle
synonyms: OIP3, PK2, PK3, PKM2
Molecular weight (observed) : 58 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, IHC, WB
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200
Research Area: Stem Cells, Cancer, Cardiovascular, Metabolism