Anti- PPARGC1B Antibody | FNab06666

Anti- PPARGC1B Antibody | FNab06666 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

Immunogen: peroxisome proliferator-activated receptor gamma, coactivator 1 beta

synonyms: PERC, PGC1, PGC1B, PPARGC1

Molecular weight (observed) : 100-110 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:1000

Research Area: Metabolism