Anti-PRAME Antibody | A1914

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

A1914 | Anti-PRAME Antibody DataSheet

Antibody Target: PRAME

Target Alternative Name: OIP4, preferentially expressed antigen in melanoma, CT130, PRAME, OIP-4, MAPE

Tag Line:

Category: Primary antibody

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human

Immunogen Sequence: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PRAME (NP_996839.1).

Accession #: P78395

Gene ID: 23532

Appearance: Liquid

Form: Liquid

Concentration:

Formulation: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification: Affinity purification

Application: Immunofluorescence (IF)

Positive Control:

Application And Usages: WB 1:500 - 1:2000, IF 1:20 - 1:50

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: False

Immunocytochemistry Verified: False

Immunofluorescence Verified: True

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False