Anti- Prealbumin/transthyretin Antibody | FNab06760

Anti- Prealbumin/transthyretin Antibody | FNab06760 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Immunogen: transthyretin

synonyms: ATTR, HsT2651, PALB, Prealbumin, TBPA, transthyretin, TTR

Molecular weight (observed) : 14 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IF, IHC

Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Research Area: Cancer, Immunology, Signal Transduction