Anti- Prealbumin/transthyretin Antibody | FNab06761

Anti- Prealbumin/transthyretin Antibody | FNab06761 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 8E4

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol, through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver, choroid plexus, retinal pigment epithelium, and pancreas.Within the CNS, TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis) . Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR), hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1) . In addition, positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. (22103483)

Immunogen: transthyretin

synonyms: ATTR, HsT2651, PALB, Prealbumin, TBPA, transthyretin, TTR

Molecular weight (observed) : 16kd

Reactivity Species: Human

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:5000; IHC: 1:20-1:200

Research Area: Cancer, Immunology, Signal Transduction