Anti- PRELID1 Antibody | FNab06766

Anti- PRELID1 Antibody | FNab06766 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.

Immunogen: PRELI domain containing 1

synonyms: CGI 106, PRELI, PRELI domain containing 1, PRELID1, PX19, Px19 like protein, SBBI12

Molecular weight (observed) : 25 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IF, WB

Recomended Dillution : IHC: 1:20-1:200

Research Area: Developmental biology