Anti- PTCH1 Antibody | FNab06910

Anti- PTCH1 Antibody | FNab06910 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH) . Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

Immunogen: patched homolog 1

synonyms: HPE7, NBCCS, Patched, patched homolog 1, Patched1, Protein patched homolog 1, PTC, PTC1, PTCH, PTCH1, PTCH11

Molecular weight (observed) : 161 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:1000; IHC: 1:50-1:200

Research Area: Neuroscience, Cell Division and Proliferation