Anti-RAD9A (RAD9) monoclonal Antibody | MB62387

Anti-RAD9A (RAD9) monoclonal Antibody | MB62387 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Dog

Application: IHC, WB

Application Range: WB 1:2000 IHC 1:50

Background: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: RAD9 checkpoint clamp component A

Molecular Weight: 42.5 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RAD9

Immunogen: Full-length protein expressed in 293T cell transfected with human RAD9A expression vector

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A