Anti-RB1 recMAb™ Antibody | A2199

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

A2199 | Anti-RB1 recMAb™ Antibody DataSheet

Antibody Target: RB1

Target Alternative Name: RB, pRb, OSRC, pp110, p105-Rb, PPP1R130, p110-RB1

Tag Line: Recombinant rabbit monoclonal antibody to detect the expression of RB1 in human and mouse samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Mouse,Human

Immunogen Sequence: Recombinant human full-length RB1 protein

Accession #: P06400

Gene ID: 5925

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In 10 mM PBS

Purification: Protein A/G purified

Application: Immunohistochemistry (IHC)

Positive Control:

Application And Usages: IHC (1-2 µg/ml)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE