710
Anti- RBBP8 Antibody | FNab07153
- SKU:
- 710-FNab07153-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- RBBP8 Antibody | FNab07153 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining (A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.
Immunogen: retinoblastoma binding protein 8
synonyms: CTIP
Molecular weight (observed) : 120 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500-1:2000
Research Area: Cell Division and Proliferation, Metabolism