Anti- RGS2 Antibody | FNab07269

Anti- RGS2 Antibody | FNab07269 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087) . Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity) . Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320) .

Immunogen: regulator of G-protein signaling 2, 24kDa

synonyms: G0S8, RGS2

Molecular weight (observed) : 24kd

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IF

Recomended Dillution : WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

Research Area: Signal Transduction