Anti-SARS-CoV-2 S2 Antibody (Clone# AbF712) | A2267

The Spike protein (S) is a type I membrane fusion protein required for viral infection and pathogenesis. It is synthesized as a precursor protein between 1200 to 1300 amino acids. The mature protein is a heavily glycosylated trimer with 21-35 glycosylation sites. Upon cleavage by host proteases, it yields 2 subunits, S1 and S2. The S1 subunit consists of 672 amino acids and is divided into 4 domains: an N-terminal domain, a C-terminal domain (also called receptor binding domain, RBD), and 2 subdomains SD1 and SD2. The S2 subunit consists of 588 amino acids and is divided into 4 domains: an N-terminal hydrophobic fusion peptide (FP), 2 heptad repeats (HR1 and HR2), a transmembrane domain (TM), and a cytoplasmic tail. When S1 recognizes and binds to the host receptor, the S2 subunit undergoes a conformational change to bring about the fusion of viral envelope and host cell membrane. Current strategies involve the development of anti-viral drugs to inhibit infection of coronavirus.

A2267 | Anti-SARS-CoV-2 S2 Antibody (Clone# AbF712) DataSheet

Antibody Target: SARS-CoV-2 Spike S2

Target Alternative Name: Spike protein, COVID19, COVID 19, S protein, SARS-CoV S protein, S glycoprotein, E2, Peplomer protein, Spike protein S1, SARS Coronavirus, SARS-CoV-2, SARS CoV 2, 2019-nCoV, Spike protein S2, S2 protein, AbF712

Tag Line: Recombinant monoclonal antibody (Clone# AbF712) to detect the expression of SARS-CoV-2 Spike S2 protein

Category: Primary antibody

Host: Recombinant

Isotype: Human IgG

Species Reactivities: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS-CoV

Immunogen Sequence: Recombinant SARS-CoV-2 S2 protein

Accession #:

Gene ID:

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In PBS, pH 7.5

Purification:

Application:

Positive Control:

Application And Usages:

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE