Anti-SCGB1A1 Antibody | A2255

Secretoglobin family 1A member 1 (SCGB1A1, CC16, CC10, Uteroglobin) is a steroid inducible, 15.8 kDa homodimeric protein that belongs to the secretoglobin family. It is secreted in large amounts from Clara cells, which are non-ciliated cells located in the respiratory and terminal bronchioles of the lungs. It is also found in other organs such as uterus, mammary gland, prostate gland and thymus. Although the exact biological function of this protein remains elusive, SCGB1A1 has been demonstrated to have both anti-inflammatory and anti-oxidative functions. SCGB1A1 can inhibit phospholipase A2 activity, as well as modulate IFN-? signaling and Th2 mediated inflammatory responses. Increased levels of SCGB1A1 occur in the plasma of patients suffering from pulmonary sarcoidosis, pulmonary fibrosis, or with injured lungs as a result of exposure to irritants such as asbestos, fire smoke, ozone. On the other hand, low levels of SCGB1A1 occur in the plasma of cigarette smokers and patients suffering from asthma and obliterative bronchiolitis. Therefore, SCGB1A1 could potentially serve as an efficient therapeutic target for the treatment of pulmonary diseases and injuries

A2255 | Anti-SCGB1A1 Antibody DataSheet

Antibody Target: SCGB1A1

Target Alternative Name: UGB, UP1, CC10, CC16, CCSP, UP-1, CCPBP, SCGB1A1

Tag Line: Rabbit polyclonal antibody to detect SCGB1A1 expression in human and mouse samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Mouse,Human

Immunogen Sequence: Recombinant full length protein of human Uteroglobin

Accession #: P11684

Gene ID: 7356

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application: Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:2000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: TRUE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE