Anti- SKP1 Antibody | FNab10039

Anti- SKP1 Antibody | FNab10039 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein (s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Immunogen: S-phase kinase-associated protein 1

synonyms: EMC19, OCP2, SKP1A, TCEB1L

Molecular weight (observed) : 19 kDa

Reactivity Species: Human, Rat

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:200 - 1:2000; IHC: 1:50 - 1:200

Research Area: Cell Division and Proliferation, Metabolism