710
Anti- SMARCA4 Antibody | FNab08005
- SKU:
- 710-FNab08005-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- SMARCA4 Antibody | FNab08005 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: SMARCA4, also named as BAF190A, BRG1, SNF2B and SNF2L4, belongs to the SNF2/RAD54 helicase family. SMARCA4 is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. It is a component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. It is also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Immunogen: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
synonyms: ATP dependent helicase SMARCA4, BAF190, BAF190A, BRG1, BRG1 associated factor 190A, FLJ39786, hSNF2b, Protein brahma homolog 1, Protein BRG 1, SMARCA4, SNF2, SNF2 BETA, SNF2B, SNF2L4, SNF2LB, SWI2, Transcription activator BRG1
Molecular weight (observed) : 185 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : WB: 1:500-1:2000; IP:1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Research Area: Epigenetics, Stem Cells, Metabolism