Anti- SORBS2 Antibody | FNab08112

Anti- SORBS2 Antibody | FNab08112 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503) . Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Immunogen: sorbin and SH3 domain containing 2

synonyms: ARGBP2, KIAA0777

Molecular weight (observed) : N/A

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB

Recomended Dillution : IP: 1:200-1:2000

Research Area: Metabolism