710
Anti- SORBS2 Antibody | FNab08112
- SKU:
- 710-FNab08112-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- SORBS2 Antibody | FNab08112 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503) . Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.
Immunogen: sorbin and SH3 domain containing 2
synonyms: ARGBP2, KIAA0777
Molecular weight (observed) : N/A
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB
Recomended Dillution : IP: 1:200-1:2000
Research Area: Metabolism