Anti- SOS1 Antibody | FNab08118

Anti- SOS1 Antibody | FNab08118 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579) . Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331) . Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity) .

Immunogen: son of sevenless homolog 1

synonyms: SOS1, GF1, GGF1, GINGF, HGF, NS4, son of sevenless homolog 1

Molecular weight (observed) : 180 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recomended Dillution : WB: 1:500 - 1:2000; IF: 1:50 - 1:100

Research Area: cancer, Signal Transduction