710
Anti- SOST Antibody | FNab08119
- SKU:
- 710-FNab08119-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- SOST Antibody | FNab08119 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Immunogen: sclerosteosis
synonyms: sclerosteosis, Sclerostin, SOST, VBCH
Molecular weight (observed) : 30 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IF
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Research Area: Signal Transduction, Metabolism, Immunology, Cancer, Stem Cells